FAQ's & Glossary

Adult Mesenchymal Stem Cells - stem cells found all over the human body and in umbilical cords, which have the ability to replicate and differentiate to form cartilage, connective tissues, muscle, fat, skin, and other cells.  Bone marrow is a common source of these cells.  However, fat tissue has an abundant source of adult mesenchymal stem cells.

Allogeneic - a source of stem cells that comes from other human bodies.

Autologous - a source of stem cells that comes from your own body; has the same DNA as host and cannot be rejected; dramatically lower risk of bacterial or viral infection.

Growth Factors - signals from damaged tissues or organs that can activate stem cell proliferation and differentiation

Regenerative Medicine - medical procedures and techniques that use stem cells and growth factors to create living, functional tissue to stimulate previously irreparable organs and tissue to heal themselves; repair or replace tissue or lost organ function due to damage or congenital defects

Stem Cell Surgery - the transfer of tissue from a stem cell rich part of the body to a damaged and stem cell deficient area of the body as a lipo-transfer surgical procedure to promote healing

Stromal Vascular Fraction (SVF) - the part of the adipose fat tissue containing the highest numbers of regenerative cells. SVF is isolated and harvested from a patient’s own fat tissue as part of minor closed surgical procedure.

What is a stem cell?

Stem cells are types of cells that can potentially become any type of cell in the body, including skin cells, muscle cells, and nerve cells. Essential characteristics of stem cells is

  1. Their ability to "self-renew" and replicate into more stem cells
  2. Their ability to differentiate and turn into other specific cells or tissues

These actions are based on signals, or growth factors, from damaged tissues. There are two types of stem cells: embryonic and adult mesenchymal.

How do stem cells work to promote healing?

The stem cells respond to injury, inflammation, degeneration, or cell death. Once activated, the stem cells may replicate into tissues or provide signals that create healing of other cells. If there is no tissue damage or injury, the stem cells remain dormant.

Doesn't stem cell therapy present moral and ethical issues?

NTX Stem Cell Treatment Center only uses adult mesenchymal stem cells derived from the patient's own fat cells to treat degenerative conditions. Adult mesenchymal stem cells are found all over the human body and in umbilical cords. Bone marrow is a common source of these cells. However, fat tissue has an abundant source of adult mesenchymal stem cells. NTX Stem Cell Treatment exclusively uses a patient's own adult mesenchymal stem cells for treatment.

What is stem cell treatment therapy?

Stromal Vascular Fraction (SVF) rich in adult mesenchymal stem cells is deployed for various conditions and diseases that are delineated on the educational web site www.stemcellrevolution.com. Specific equipment has been modified and branded (Time Machine™) to allow specially trained and certified physicians to deploy SVF as a surgical procedure in an outpatient setting.

How are stem cells deployed or transferred?

The stem cells are injected directly into the affected joint or tissues showing damage.

Is stem cell treatment therapy approved by the FDA?

STEM CELL TREATMENT IS NOT APPROVED BY THE FDA FOR ANY SPECIFIC DISEASE. NTX Stem Cell does NOT claim that any applications, or potential applications, using these autologous stem cell treatments are approved by the FDA, or are even effective. We do not claim that these treatments work for any listed nor unlisted condition, intended or implied. It is important for patients to do their own research based on the options that we present, so that one can make an informed decision.

Why use stem cells derived from fat versus bone marrow from blood?

Bone marrow mesenchymal stem cells decline with age. Please see the charts below.

Bone marrow

Bone marrow

How safe is stem cell treatment?

The stem cell treatment procedure is autologous, meaning the cells come from the patient's own body. Special equipment is used to harvest and deploy the stem cells from the patient's own body. The entire procedure is performed in office, and there is no shipping or transport of the stem cells to an outside lab. The entire procedure is performed in approximately 3 hours and on the same day. The procedure is safe and has a significantly lower risk of infection and/or rejection of the cells as the patient's own cells are being used.

What are the risks of stem cell treatment?

Every surgical procedure presents some level of risk. However, stem cell treatment involves a dramatically lower degree of risk of infection and other complications.

Cell Surgical Network® has performed over 2000 cases with zero serious complications. Cell Surgical Network® is submitting its first 1000 cases for publication. There are no documented cases of serious injury to human or animals.

International Cell Medicine Society (ICMS) reported over 1,000 registered cases with less than 2% complications of any kind and no serious adverse events.

How many treatments are required?

The number of treatments depends on the condition being treated. Stem cells can be preserved for future use through cryopreservation.

How successful is stem cell treatment?

Patient outcomes may vary, but patients have reported decreased pain and increased mobility after the first injection. Patients have experienced quicker recovery for knees (improvement within 2 months), shoulders (improvement within 3 months), hand/wrist (improvement within days), backs and hips (improvement within weeks). Stem cell treatment avoids the morbidity and risks associated with total joint replacement surgery and other surgical procedures.

How do I know if I am a candidate for stem cell treatment?

Not all patients are a candidate for stem cell treatment. Contact NTX Stem Cell Treatment Center to determine if you're a candidate. A physician will consult with you to discuss your medical history, medical needs, the possibility of success, and the cost of the procedure.

Who is a candidate for this treatment?

In general, these treatments are advised for patients who have pain secondary to moderate osteoarthritis in the hip, knee, shoulder, ankle, or thumb, where there is not complete collapse of the joint space and not “bone on bone” changes. Stem cell therapy is also done for soft tissue injuries such as tears and chronic or severe tendinosis.

Who is not a candidate for these types of treatments?

  • Patients with a blood borne Cancer (such as lymphoma or leukemia), not in remission for at least 5 years
  • Patients undergoing treatment for other malignancies or blood borne diseases
  • Patients with an active infection
  • Patient who are on a high dose of Coumadin or other blood thinner
  • Patients with multiple medical issues may not be good candidates (low testosterone, low vitamin D, Hypothyroidism, Diabetes, smoker)

**This a partial list; there may be other conditions that limit your stem cell candidacy.

If I am a candidate for stem cell treatment, how do I prepare for the procedure?

Pre-operative written instructions and medication instructions are sent to patients. Labs can be ordered if appropriate. Out of town patients are instructed to come into the area one day prior and stay until the day following their procedure. Although this is a minor procedure involving a small puncture, patients can be expected to be "sore" for a couple days.

What should I expect on the day of procedure?

On procedure day, patients check in and complete payment arrangements if appropriate. They then meet the clinical research coordinator who obtains baseline subjective testing and the necessary consent and privacy forms. Physicians will perform a brief history and physical and answering questions. The goal is to confirm the treatment plan and do a simple check of heart and lungs. Patients are then taken to the treatment room where the surgical assistant (RN, CST, or physician assistant) and the treating physician will greet them, confirm allergies, treatment plan, site for harvesting and eventual deployment. Once this is confirmed, the patient is prepared for mini liposuction.

What does the procedure entail?

After injecting local anesthetic, fat is obtained via syringe liposuction and a pressure dressing is placed. Next, the patient is taken to a comfortable room to rest, have juice or a snack or even dismissed for 45 minutes - 1 hour for a coffee break, etc. and given a time to return for further treatment (e.g. start IV, harvest blood for PRP, or deployment of SVF). Once fat has been harvested the remaining process takes about 1 hour. When SVF is ready, a sample is given to the physician to count the cells and check cell viability (normal viability is 75%-85%). SVF deployment is performed according to prescribed protocols and the condition being treated by the treatment team. Patients are then given discharge instructions, contact information and sent home. Patients are contacted within 24 hours by a nurse to check on them.

How much does the procedure cost?

At this time, the cost of stem cell treatments is not covered by insurance companies. We are patient funded and we have no source of grants or pharmaceutical company funding. We have set our fees very reasonably to increase access to stem cell medicine. Our fee includes harvesting, isolating cells and deployment of your own cells. Also, under special conditions, your stem cells maybe cryogenically stored for future treatments.

Which joints or body parts can stem cells or fat tissue be injected?

Most commonly injections are for larger joints, such as hips and knees, but we also treat shoulders, ankles, and smaller joints in the hand or feet with these therapies. Stem cell treatments are also an option for chronic tendon issues that have been resistant to platelet rich plasma (PRP), steroid injections, and other treatments. These are typically done in the rotator cuff, lateral elbow, Achilles tendons, and other select tissues.

Can I fly / drive home that day?

A patient may fly home the same day (if the patient is not the pilot). Patients should be aware there they will experience some increased pain/discomfort after the procedure. Patients driving home should have a driver to take them home following the procedure.

What should I do if I think I’m a candidate?

If you live within 3 hours of Atlanta, we will schedule a consultation for an appointment to review your radiology films (x-rays), conduct a physical exam, and determine if you are a good candidate or not. If you live more than 3 hours away, please work with your local health care professional to send us the following:

Download and print this form: Complete it and include with the other records you are sending. *Recent x-rays, no more than a few months old, are required. *Please see below for the type of x-ray views needed for the effected body parts.

  • Hip - Standing AP pelvis and frog lateral
  • Knee - Standing bilateral AP and lateral
  • Ankle - Standing AP, lateral and oblique
  • Shoulder - Grashey and axillary lateral
  • Thumb - AP, lateral and oblique
  • Recent MRI if available, no more than a few months’ old
  • Medical records (only pertaining to your injury for which you are seeking treatment)

Send your images and records to us for review:

Please include your name, address, phone number and email address. We will contact you with our recommendation within 7-14 business days of receiving your records.

Send your documents and images to:

North Texas Stem Cell Treatment Center
8080 State Hwy 121
Suite 320
McKinney, TX 75025

Patient Education / Appointment

You may be considering stem cell therapy for a particular condition or your physician may be treating you for a condition that he/she feels might respond well to stem cell therapy. Contact NTX Stem Cell Treatment Center to schedule an initial consultation at: ntxstemcells@osmortho.com or 1 888 371 5925.